Order NO. D198859
产品描述
概述
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
应用
免疫印迹(WB),免疫荧光(IF)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P25963
|
靶点基因 ID |
4792
|
靶点全称 |
NFKB inhibitor alpha
|
靶点别名 |
IKBA; MAD-3; NFKBI; EDAID2
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling, Immunology
|
亚型 |
IgG1
|