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Order NO. D198908
小鼠抗POU5F1单克隆抗体
英文名 Anti-POU5F1 mouse monoclonal antibody
别名 Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human , Rat , Mouse
克隆类型 mouse monoclonal 抗原 POU5F1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D198908-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

应用

免疫印迹(WB),免疫荧光(IF)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q01860
靶点基因 ID 5460
靶点全称 POU class 5 homeobox 1
靶点别名 OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4
靶点研究领域 Epigenetics and Nuclear Signaling, Stem Cells, Developmental Biology
亚型 IgG1
相关文档
Sample Application

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D198908(POU5F1 Antibody) at dilution 1/100

  • Gel: 10%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D198908(POU5F1 Antibody) at dilution 1/200, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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