Order NO. D198908
产品描述
概述
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
应用
免疫印迹(WB),免疫荧光(IF)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q01860
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靶点基因 ID |
5460
|
靶点全称 |
POU class 5 homeobox 1
|
靶点别名 |
OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4
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靶点研究领域 |
Epigenetics and Nuclear Signaling, Stem Cells, Developmental Biology
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亚型 |
IgG1
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