Order NO. D198957
产品描述
概述
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
应用
免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
O00429
|
靶点基因 ID |
10059
|
靶点全称 |
dynamin 1 like
|
靶点别名 |
DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV
|
靶点研究领域 |
Metabolism, Cancer, Neuroscience
|
亚型 |
IgG2b
|