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Order NO. D198963
小鼠抗CD3E单克隆抗体
英文名 Anti-CD3E mouse monoclonal antibody
别名 IMD18; T3E; TCRE
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human , Dog , Monkey
克隆类型 mouse monoclonal 抗原 CD3E
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D198963-0100 100 ul 预计5日内发货
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产品描述

概述

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P07766
靶点基因 ID 916
靶点全称 CD3e molecule
靶点别名 T3E; TCRE; IMD18
靶点研究领域 Immunology, Stem Cells
亚型 IgG2b
相关文档
Sample Application

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D198963(CD3E Antibody) at dilution 1/100

  • The image on the left is immunohistochemistry of paraffin-embedded human liver tissue, on the right is immunohistochemistry of paraffin-embedded human lymphoma tissue using D198963(CD3E Antibody) at dilution 1/40. (Original magnification: ×200)


  • Gel: 12%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D198963(CD3E Antibody) at dilution 1/200, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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