概述

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.

应用

免疫印迹（WB），免疫组织化学（IHC），免疫荧光（IF）

属性

保存缓冲液	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件	2-8°C
靶点 Uniprot 登记号	P10144
靶点基因 ID	3002
靶点全称	granzyme B
靶点别名	C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1
靶点研究领域	Cancer, Immunology
亚型	IgG1