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Order NO. D199227
小鼠抗FMR1单克隆抗体
英文名 Anti-FMR1 mouse monoclonal antibody
别名 FMRP; FRAXA; POF; POF1; POFX
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human , Dog , Rat , Monkey , Mouse
克隆类型 mouse monoclonal 抗原 FMR1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199227-0100 100 ul 预计5日内发货
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产品描述

概述

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF),流式细胞术(FCM)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q06787
靶点基因 ID 2332
靶点全称 FMRP translational regulator 1
靶点别名 POF; FMRP; POF1; FRAXA
靶点研究领域 Epigenetics and Nuclear Signaling, Neuroscience
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis using D199227(FMR1 antibody) at dilution 1/100, staining Jurkat cells(Red), compared to a nonspecific negative control antibody(Blue)

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D199227(FMR1 Antibody) at dilution 1/100

  • The image on the left is immunohistochemistry of paraffin-embedded adenocarcinoma of human breast tissue, on the right is immunohistochemistry of paraffin-embedded human colon tissue using D199227(FMR1 Antibody) at dilution 1/40. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded adenocarcinoma of human colon tissue, on the right is immunohistochemistry of paraffin-embedded human Kidney tissue using D199227(FMR1 Antibody) at dilution 1/40. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199227(FMR1 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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