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Order NO. D199321
小鼠抗ASCC1单克隆抗体
英文名 Anti-ASCC1 mouse monoclonal antibody
别名 ASC1p50; CGI-18; RP11-150D20.4
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 ASCC1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199321-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF),流式细胞术(FCM)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q8N9N2
靶点基因 ID 51008
靶点全称 activating signal cointegrator 1 complex subunit 1
靶点别名 p50; CGI-18; SMABF2; ASC1p50
靶点研究领域 Signal Transduction
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis using D199321(ASCC1 antibody) at dilution 1/100, staining Jurkat cells(Red), compared to a nonspecific negative control antibody(Blue)

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D199321(ASCC1 Antibody) at dilution 1/100

  • The image is immunohistochemistry of paraffin-embedded human tonsil using D199321(ASCC1 Antibody) at dilution 1/40. (Original magnification: ×200)

  • Gel: 10%SDS-PAGE, Lysate: 10μg, Lane 1-4: Hela, A549, COS7, Jurkat cell lysates, Primary antibody: D199321(ASCC1 Antibody) at dilution 1/200, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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