Order NO. D199328
产品描述
概述
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
应用
免疫印迹(WB),免疫荧光(IF)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q8N6T7
|
靶点基因 ID |
51548
|
靶点全称 |
sirtuin 6
|
靶点别名 |
SIR2L6
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Signal Transduction, Metabolism, Cardiovascular
|
亚型 |
IgG1
|