概述

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

应用

免疫印迹（WB），免疫荧光（IF），流式细胞术（FCM）

属性

保存缓冲液	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件	2-8°C
靶点 Uniprot 登记号	O15315
靶点基因 ID	5890
靶点全称	RAD51 paralog B
靶点别名	REC2; R51H2; RAD51L1
靶点研究领域	Epigenetics and Nuclear Signaling
亚型	IgG1