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Order NO. D199392
小鼠抗PSMD2单克隆抗体
英文名 Anti-PSMD2 mouse monoclonal antibody
别名 P97; RPN1; S2; TRAP2
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human , Dog , Rat , Monkey , Mouse
克隆类型 mouse monoclonal 抗原 PSMD2
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199392-0100 100 ul 预计5日内发货
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产品描述

概述

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q13200
靶点基因 ID 5708
靶点全称 proteasome 26S subunit, non-ATPase 2
靶点别名 S2; P97; RPN1; TRAP2
靶点研究领域 Cell Biology
亚型 IgG2a
相关文档
Sample Application

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D199392(PSMD2 Antibody) at dilution 1/100

  • The image on the left is immunohistochemistry of paraffin-embedded human Kidney tissue, on the right is immunohistochemistry of paraffin-embedded human pancreas tissue using D199392(PSMD2 Antibody) at dilution 1/40. (Original magnification: ×200)


  • The image is immunohistochemistry of paraffin-embedded human lymphoma tissue using D199392(PSMD2 Antibody) at dilution 1/40. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199392(PSMD2 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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