Order NO. D199433
产品描述
概述
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用
免疫印迹(WB),免疫荧光(IF),流式细胞术(FCM)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q9UQQ2
|
靶点基因 ID |
10019
|
靶点全称 |
SH2B adaptor protein 3
|
靶点别名 |
LNK; IDDM20
|
靶点研究领域 |
Immunology, Signal Transduction
|
亚型 |
IgG1
|