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Order NO. D199437
小鼠抗RPS6KB1单克隆抗体
英文名 Anti-RPS6KB1 mouse monoclonal antibody
别名 p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 RPS6KB1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199437-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF),流式细胞术(FCM)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P23443
靶点基因 ID 6198
靶点全称 ribosomal protein S6 kinase B1
靶点别名 S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha
靶点研究领域 Signal Transduction, Epigenetics and Nuclear Signaling, Metabolism, Cancer
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis using D199437(RPS6KB1 antibody) at dilution 1/100, staining Jurkat cells(Red), compared to a nonspecific negative control antibody(Blue)

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D199437(RPS6KB1 Antibody) at dilution 1/100

  • The image on the left is immunohistochemistry of paraffin-embedded human pancreas tissue, on the right is immunohistochemistry of paraffin-embedded adenocarcinoma of human endometrium tissue using D199437(RPS6KB1 Antibody) at dilution 1/40. (Original magnification: ×200)


  • The image is immunohistochemistry of paraffin-embedded carcinoma of human prostate tissue using D199437(RPS6KB1 Antibody) at dilution 1/40. (Original magnification: ×200)

  • Gel: 10%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199437(RPS6KB1 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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