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Order NO. D199560
小鼠抗HDAC1单克隆抗体
英文名 Anti-HDAC1 mouse monoclonal antibody
别名 GON-10; HD1; RPD3; RPD3L1
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human , Rat , Monkey
克隆类型 mouse monoclonal 抗原 HDAC1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199560-0100 100 ul 预计5日内发货
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产品描述

概述

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

应用

免疫印迹(WB),免疫荧光(IF),流式细胞术(FCM)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q13547
靶点基因 ID 3065
靶点全称 histone deacetylase 1
靶点别名 HD1; RPD3; KDAC1; GON-10; RPD3L1
靶点研究领域 Epigenetics and Nuclear Signaling, Cardiovascular, Signal Transduction
亚型 IgG2b
相关文档
Sample Application

  • The image is flow cytometry analysis using D199560(HDAC1 antibody) at dilution 1/100, staining HEK293T cells transfected with either overexpress plasmid(Red) or empty vector control plasmid(Blue)

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D199560(HDAC1 Antibody) at dilution 1/100

  • Gel: 10%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, HT-29, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199560(HDAC1 Antibody) at dilution 1/200, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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