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Order NO. D199564
小鼠抗SQSTM1单克隆抗体
英文名 Anti-SQSTM1 mouse monoclonal antibody
别名 A170; OSIL; p60; p62; p62B; PDB3; ZIP3
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 SQSTM1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199564-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF),流式细胞术(FCM)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q13501
靶点基因 ID 8878
靶点全称 sequestosome 1
靶点别名 p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3
靶点研究领域 Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Cardiovascular
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis using D199564(SQSTM1 antibody) at dilution 1/100, staining HEK293T cells transfected with either overexpress plasmid(Red) or empty vector control plasmid(Blue)

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D199564(SQSTM1 Antibody) at dilution 1/100

  • The image on the left is immunohistochemistry of paraffin-embedded human Ovary tissue, on the right is immunohistochemistry of paraffin-embedded human lymph node tissue using D199564(SQSTM1 Antibody) at dilution 1/40. (Original magnification: ×200)


  • The image is immunohistochemistry of paraffin-embedded human lymphoma tissue using D199564(SQSTM1 Antibody) at dilution 1/40. (Original magnification: ×200)

  • Gel: 10%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, HT-29, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199564(SQSTM1 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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