Order NO. D199564
产品描述
概述
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
应用
免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF),流式细胞术(FCM)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q13501
|
靶点基因 ID |
8878
|
靶点全称 |
sequestosome 1
|
靶点别名 |
p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Cardiovascular
|
亚型 |
IgG1
|