Order NO. D199597
产品描述
概述
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
应用
免疫印迹(WB)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P04179
|
靶点基因 ID |
6648
|
靶点全称 |
superoxide dismutase 2
|
靶点别名 |
IPOB; IPO-B; MNSOD; MVCD6; GClnc1; Mn-SOD
|
靶点研究领域 |
Metabolism, Cancer, Cardiovascular, Neuroscience
|
亚型 |
IgG1
|