Order NO. D199619
产品描述
概述
Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
应用
免疫印迹(WB),免疫荧光(IF),流式细胞术(FCM)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q6ZUJ8
|
靶点基因 ID |
118788
|
靶点全称 |
phosphoinositide-3-kinase adaptor protein 1
|
靶点别名 |
BCAP
|
靶点研究领域 |
Cell Biology
|
亚型 |
IgG1
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