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Order NO. D199812
小鼠抗HSD17B10单克隆抗体
英文名 Anti-HSD17B10 mouse monoclonal antibody
别名 17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD;
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 HSD17B10
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199812-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF),流式细胞术(FCM)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q99714
靶点基因 ID 3028
靶点全称 hydroxysteroid 17-beta dehydrogenase 10
靶点别名 ABAD; CAMR; ERAB; HCD2; MHBD; HADH2; MRPP2; MRX17; MRX31; SCHAD; MRXS10; SDR5C1; HSD10MD; 17b-HSD10; DUPXp11.22
靶点研究领域 Metabolism, Neuroscience
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis using D199812(HSD17B10 antibody) at dilution 1/100, staining Hela cells(Red), compared to a nonspecific negative control antibody(Blue)

  • The image is immunofluorescence of COS7 cells transiently transfected by pCMV6-ENTRY using D199812(HSD17B10 Antibody) at dilution 1/100

  • The image on the left is immunohistochemistry of paraffin-embedded liver tissue, on the right is immunohistochemistry of paraffin-embedded carcinoma of liver tissue using D199812(HSD17B10 Antibody) at dilution 1/40. (Original magnification: ×200)


  • Gel: 12%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, HT-29, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199812(HSD17B10 Antibody) at dilution 1/1000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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