Order NO. D199859
产品描述
概述
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
应用
免疫印迹（WB），免疫组织化学（IHC），流式细胞术（FCM）
属性
| 保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
P00441
|
| 靶点基因 ID |
6647
|
| 靶点全称 |
superoxide dismutase 1
|
| 靶点别名 |
ALS; SOD; ALS1; IPOA; STAHP; hSod1; HEL-S-44; homodimer
|
| 靶点研究领域 |
Signal Transduction, Cancer, Metabolism, Cell Biology
|
| 亚型 |
IgG2b
|
