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Order NO. D199929
小鼠抗PDX1单克隆抗体
英文名 Anti-PDX1 mouse monoclonal antibody
别名 GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 PDX1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199929-0100 100 ul 预计5日内发货
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产品描述

概述

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

应用

免疫印迹(WB)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P52945
靶点基因 ID 3651
靶点全称 pancreatic and duodenal homeobox 1
靶点别名 GSF; IPF1; IUF1; IDX-1; MODY4; PDX-1; STF-1; PAGEN1
靶点研究领域 Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Metabolism, Cardiovascular, Developmental Biology
亚型 IgG1
相关文档
Sample Application

  • Gel: 10%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, HT-29, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199929(PDX1 Antibody) at dilution 1/5000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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