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Order NO. D199936
小鼠抗KRT8单克隆抗体
英文名 Anti-KRT8 mouse monoclonal antibody
别名 CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human, Dog, Rat, Monkey
克隆类型 mouse monoclonal 抗原 KRT8
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D199936-0100 100 ul 预计5日内发货
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产品描述

概述

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P05787
靶点基因 ID 3856
靶点全称 keratin 8
靶点别名 K8; KO; CK8; CK-8; CYK8; K2C8; CARD2
靶点研究领域 Signal Transduction, Cancer
亚型 IgG2b
相关文档
Sample Application

  • The image is immunofluorescence of A549 cells using D199936(KRT8 Antibody) at dilution 1/50

  • The image is immunohistochemistry of paraffin-embedded human liver tissue using D199936(KRT8 Antibody) at dilution 1/40. (Original magnification: ×200)

  • Gel: 10%SDS-PAGE, Lysate: 35μg, Lane 1-9: HepG2, Hela, HT-29, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates, Primary antibody: D199936(KRT8 Antibody) at dilution 1/2500, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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