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Order NO. D220073
兔抗BAX多克隆抗体
英文名 Anti-BAX rabbit polyclonal antibody
别名 BCL2L4
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 BAX    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D220073-0025 25 ul 现货
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D220073-0100 100 ul 现货
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D220073-0200 200 ul 现货
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属性

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, WB, IHC
Name of antibody: BAX
Immunogen: Recombinant protein of human BAX
Full name: BCL2 associated X, apoptosis regulator
Synonyms: BCL2L4
SwissProt: Q07812
ELISA Recommended dilution: 5000-10000
IHC positive control: Human colorectal cancer
IHC Recommend dilution: 50-200
WB Predicted band size: 21 kDa
WB Positive control: LOVO, A549, RAW264.7, Raji cell lysates
WB Recommended dilution: 1000-5000
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using D220073(BAX Antibody) at dilution 1/70, on the right is treated with recombinant protein. (Original magnification: ×200)


  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: LOVO, A549, RAW264.7, Raji cell lysates, Primary antibody: D220073(BAX Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 1 second
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