Order NO. D220073
兔抗BAX多克隆抗体
英文名 | Anti-BAX rabbit polyclonal antibody | ||
别名 | BCL2L4 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
抗原 | BAX | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D220073-0025 | 25 ul | 现货 |
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D220073-0100 | 100 ul | 现货 |
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D220073-0200 | 200 ul | 现货 |
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属性
Background: | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019] (The background information is obtained from official databases and does not represent the product information.) |
Applications: | ELISA, WB, IHC |
Name of antibody: | BAX |
Immunogen: | Recombinant protein of human BAX |
Full name: | BCL2 associated X, apoptosis regulator |
Synonyms: | BCL2L4 |
SwissProt: | Q07812 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human colorectal cancer |
IHC Recommend dilution: | 50-200 |
WB Predicted band size: | 21 kDa |
WB Positive control: | LOVO, A549, RAW264.7, Raji cell lysates |
WB Recommended dilution: | 1000-5000 |