网 站
反 馈
网 站
指 南
Order NO. D220162
兔抗IL10RA多克隆抗体
英文名 Anti-IL10RA rabbit polyclonal antibody
别名 CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 IL10RA
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D220162-0025 25 ul 现货
加入购物车
D220162-0100 100 ul 现货
加入购物车
D220162-0200 200 ul 现货
加入购物车
产品描述

概述

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q13651
靶点基因 ID 3587
靶点全称 Interleukin-10 receptor subunit alpha
靶点别名 CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1
靶点研究领域 Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tosil tissue using D220162(IL10RA Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)

    我的购物车(0) 结算