Order NO. D221009
产品描述
概述
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q99836
|
靶点基因 ID |
4615
|
靶点全称 |
MYD88 innate immune signal transduction adaptor
|
靶点别名 |
WM1; IMD68; MYD88D
|
靶点研究领域 |
Signal Transduction, Cardiovascular, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|