Order NO. D221221
产品描述
概述
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q8IXJ6
|
靶点基因 ID |
22933
|
靶点全称 |
sirtuin 2
|
靶点别名 |
SIR2; SIR2L; SIR2L2
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling
|
亚型 |
Immunogen-specific rabbit IgG
|