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Order NO. D221482
兔抗ACVR2A多克隆抗体
英文名 Anti-ACVR2A rabbit polyclonal antibody
别名 ACVR2; ACTRII
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 ACVR2A
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D221482-0025 25 ul 现货
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D221482-0100 100 ul 现货
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D221482-0200 200 ul 现货
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产品描述

概述

This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P27037
靶点基因 ID 92
靶点全称 Activin A receptor, type IIA
靶点别名 ACVR2; ACTRII
靶点研究领域 Metabolism, Signal Transduction
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: D221482(ACVR2A Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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