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Order NO. D221501
兔抗ADAM15多克隆抗体
英文名 Anti-ADAM15 rabbit polyclonal antibody
别名 MDC15
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 ADAM15
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D221501-0025 25 ul 现货
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D221501-0100 100 ul 现货
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D221501-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q13444
靶点基因 ID 8751
靶点全称 ADAM metallopeptidase domain 15
靶点别名 MDC15
靶点研究领域 Signal Transduction, Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D221501(ADAM15 Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: NIH/3T3, HepG2, PC-3, Jurkat cell, Mouse heart tissue lysates, Primary antibody: D221501(ADAM15 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 minutes