Order NO. D221881
兔抗BAP1多克隆抗体
| 英文名 | Anti-BAP1 rabbit polyclonal antibody | ||
| 别名 | UCHL2; hucep-6; HUCEP-13 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | BAP1 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D221881-0025 | 25 ul | 现货 |
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| D221881-0100 | 100 ul | 现货 |
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| D221881-0200 | 200 ul | 现货 |
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产品描述
概述
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q92560 |
| 靶点基因 ID | 8314 |
| 靶点全称 | BRCA1 associated protein 1 |
| 靶点别名 | UCHL2; hucep-6; HUCEP-13 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling, Cancer |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
