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Order NO. D222184
兔抗CYP17A1多克隆抗体
英文名 Anti-CYP17A1 rabbit polyclonal antibody
别名 CPT7; CYP17; S17AH; P450C17
相关类别 一抗 储存 冷冻（-20℃）
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 CYP17A1
编 号 规格 库存 目录价（￥） 您的价格（￥） 数 量
D222184-0025 25 ul 现货 500 500
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D222184-0100 100 ul 现货 1600 1600
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D222184-0200 200 ul 现货 2500 2500
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产品描述

概述

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

应用

酶联免疫吸附测定（ELISA），免疫组织化学（IHC）

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P05093
靶点基因 ID 1586
靶点全称 cytochrome P450, family 17, subfamily A, polypeptide 1
靶点别名 CPT7; CYP17; S17AH; P450C17
靶点研究领域 Metabolism, Signal Transduction, Cancer, Cardiovascular
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D222184(CYP17A1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D222184(CYP17A1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)