Order NO. D222399
产品描述
概述
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
O75293
|
靶点基因 ID |
4616
|
靶点全称 |
growth arrest and DNA-damage-inducible, beta
|
靶点别名 |
MYD118; GADD45BETA
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|