Order NO. D222948
产品描述
概述
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q16849
|
靶点基因 ID |
5798
|
靶点全称 |
protein tyrosine phosphatase receptor type N
|
靶点别名 |
IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP
|
靶点研究领域 |
Signal Transduction, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|