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Order NO. D223285
兔抗MAP3K7多克隆抗体
英文名 Anti-MAP3K7 rabbit polyclonal antibody
别名 TAK1; MEKK7; TGF1a
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 MAP3K7
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D223285-0025 25 ul 现货
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D223285-0100 100 ul 现货
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D223285-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 O43318
靶点基因 ID 6885
靶点全称 mitogen-activated protein kinase kinase kinase 7
靶点别名 CSCF; FMD2; TAK1; MEKK7; TGF1a
靶点研究领域 Signal Transduction, Cardiovascular, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D223285(MAP3K7 Antibody) at dilution 1/150, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-5: 231, 293T, HepG2, Jurkat and K562 cell lysates, Primary antibody: D223285(MAP3K7 Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 1 minute
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