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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D224053-0025 | 25 ul | 现货 |
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| D224053-0100 | 100 ul | 现货 |
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| D224053-0200 | 200 ul | 现货 |
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概述
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q15942 |
| 靶点基因 ID | 7791 |
| 靶点全称 | zyxin |
| 靶点别名 | ESP-2; HED-2 |
| 靶点研究领域 | Signal Transduction, Epigenetics and Nuclear Signaling, Neuroscience |
| 亚型 | Immunogen-specific rabbit IgG |
