Order NO. D224134
产品描述
概述
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P61077
|
靶点基因 ID |
7323
|
靶点全称 |
ubiquitin conjugating enzyme E2D 3
|
靶点别名 |
UBC4/5; UBCH5C; E2(17)KB3
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cell Biology
|
亚型 |
Immunogen-specific rabbit IgG
|