Order NO. D225037
产品描述
概述
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P12643
|
靶点基因 ID |
650
|
靶点全称 |
bone morphogenetic protein 2
|
靶点别名 |
BDA2; BMP2A; SSFSC; SSFSC1
|
靶点研究领域 |
Signal Transduction, Cancer, Cardiovascular, Stem Cells
|
亚型 |
Immunogen-specific rabbit IgG
|