Order NO. D225080
兔抗SHC1多克隆抗体
| 英文名 | Anti-SHC1 rabbit polyclonal antibody | ||
| 别名 | SHC adaptor protein 1; SHC; SHCA | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | SHC1 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D225080-0025 | 25 ul | 现货 |
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| D225080-0100 | 100 ul | 现货 |
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| D225080-0200 | 200 ul | 现货 |
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产品描述
概述
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P29353 |
| 靶点基因 ID | 6464 |
| 靶点全称 | SHC adaptor protein 1 |
| 靶点别名 | SHC; SHCA |
| 靶点研究领域 | Signal Transduction, Neuroscience |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
