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Order NO. D225873
兔抗IFT57多克隆抗体
英文名 Anti-IFT57 rabbit polyclonal antibody
别名 intraflagellar transport 57; HIPPI; MHS4R2; ESRRBL1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 IFT57
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D225873-0025 25 ul 现货
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D225873-0100 100 ul 现货
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D225873-0200 200 ul 现货
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产品描述

概述

Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q9NWB7
靶点基因 ID 55081
靶点全称 intraflagellar transport 57
靶点别名 HIPPI; MHS4R2; ESRRBL1
靶点研究领域 Neuroscience
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D225873(IFT57 Antibody) at dilution 1/85, on the right is treated with fusion protein. (Original magnification: ×200)

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