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编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D225915-0025 | 25 ul | 现货 |
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D225915-0100 | 100 ul | 现货 |
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D225915-0200 | 200 ul | 现货 |
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概述
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | P43403 |
靶点基因 ID | 7535 |
靶点全称 | zeta chain of T cell receptor associated protein kinase 70 |
靶点别名 | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 |
靶点研究领域 | Signal Transduction, Immunology |
亚型 | Immunogen-specific rabbit IgG |