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Order NO. D225915
兔抗ZAP70多克隆抗体
英文名 Anti-ZAP70 rabbit polyclonal antibody
别名 zeta chain of T cell receptor associated protein kinase 70; SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 ZAP70
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D225915-0025 25 ul 现货
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D225915-0100 100 ul 现货
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D225915-0200 200 ul 现货
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产品描述

概述

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P43403
靶点基因 ID 7535
靶点全称 zeta chain of T cell receptor associated protein kinase 70
靶点别名 SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
靶点研究领域 Signal Transduction, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D225915(ZAP70 Antibody) at dilution 1/55, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse liver tissue and Jurkat cell lysates, Primary antibody: D225915(ZAP70 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes
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