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Order NO. D226143
兔抗MRPL40多克隆抗体
英文名 Anti-MRPL40 rabbit polyclonal antibody
别名 mitochondrial ribosomal protein L40; URIM; L40mt; NLVCF; MRPL22; MRP-L22; MRP-L40
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 MRPL40
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D226143-0025 25 ul 现货
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D226143-0100 100 ul 现货
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D226143-0200 200 ul 现货
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产品描述

概述

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q9NQ50
靶点基因 ID 64976
靶点全称 mitochondrial ribosomal protein L40
靶点别名 URIM; L40mt; NLVCF; MRPL22; MRP-L22; MRP-L40
靶点研究领域 Epigenetics and Nuclear Signaling
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using D226143(MRPL40 Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using D226143(MRPL40 Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: K562, A172, Jurkat, LOVO cell lysates, Primary antibody: D226143(MRPL40 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute