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Order NO. D226220
兔抗RAB3IP多克隆抗体
英文名 Anti-RAB3IP rabbit polyclonal antibody
别名 RAB3A interacting protein; RABIN3; RABIN8
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 RAB3IP
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D226220-0025 25 ul 现货
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D226220-0100 100 ul 现货
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D226220-0200 200 ul 现货
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产品描述

概述

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q96QF0
靶点基因 ID 117177
靶点全称 RAB3A interacting protein
靶点别名 RABIN3; RABIN8
靶点研究领域 Signal Transduction, Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D226220(RAB3IP Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)

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