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Order NO. D226556
兔抗SAV1多克隆抗体
英文名 Anti-SAV1 rabbit polyclonal antibody
别名 salvador family WW domain containing protein 1; SAV; WW45; WWP4
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 SAV1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D226556-0025 25 ul 现货
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D226556-0100 100 ul 现货
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D226556-0200 200 ul 现货
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产品描述

概述

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q9H4B6
靶点基因 ID 60485
靶点全称 salvador family WW domain containing protein 1
靶点别名 SAV; WW45; WWP4
靶点研究领域 Signal Transduction
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using D226556(SAV1 Antibody) at dilution 1/90, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D226556(SAV1 Antibody) at dilution 1/90, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HUVEC, PC-3 cell lysates, Primary antibody: D226556(SAV1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute
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