Order NO. D227430
产品描述
概述
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P27986
|
靶点基因 ID |
5295
|
靶点全称 |
phosphoinositide-3-kinase regulatory subunit 1
|
靶点别名 |
p85; AGM7; GRB1; IMD36; p85-ALPHA
|
靶点研究领域 |
Signal Transduction, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|