Order NO. D227690
产品描述
概述
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB）
属性
| 保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
Q13133
|
| 靶点基因 ID |
10062
|
| 靶点全称 |
nuclear receptor subfamily 1 group H member 3
|
| 靶点别名 |
LXRA; LXR-a; RLD-1
|
| 靶点研究领域 |
Cardiovascular, Signal Transduction, Epigenetics and Nuclear Signaling, Signal Transduction, Cancer, Metabolism
|
| 亚型 |
Immunogen-specific rabbit IgG
|
