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Order NO. D227690
兔抗NR1H3多克隆抗体
英文名 Anti-NR1H3 rabbit polyclonal antibody
别名 nuclear receptor subfamily 1 group H member 3; LXRA; LXR-a; RLD-1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 NR1H3
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D227690-0025 25 ul 现货
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D227690-0100 100 ul 现货
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D227690-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q13133
靶点基因 ID 10062
靶点全称 nuclear receptor subfamily 1 group H member 3
靶点别名 LXRA; LXR-a; RLD-1
靶点研究领域 Cardiovascular, Signal Transduction, Epigenetics and Nuclear Signaling, Signal Transduction, Cancer, Metabolism
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse kidney tissue, Mouse liver tissue lysates, Primary antibody: D227690(NR1H3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute
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