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Order NO. D227880
兔抗STING1多克隆抗体
英文名 Anti-STING1 rabbit polyclonal antibody
别名 stimulator of interferon response cGAMP interactor 1; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 STING1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D227880-0025 25 ul 现货
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D227880-0100 100 ul 现货
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D227880-0200 200 ul 现货
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产品描述

概述

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q86WV6
靶点基因 ID 340061
靶点全称 stimulator of interferon response cGAMP interactor 1
靶点别名 ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta
靶点研究领域 Immunology, Signal Transduction, Epigenetics and Nuclear Signaling
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D227880(STING1 Antibody) at dilution 1/100, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using D227880(STING1 Antibody) at dilution 1/100, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: K562 cell lysate, Primary antibody: D227880(STING1 Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 1 second
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