Order NO. D260008
兔抗APAF1多克隆抗体
| 英文名 | Anti-APAF1 rabbit polyclonal antibody | ||
| 别名 | CED4 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | APAF1 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D260008-0025 | 25 ul | 现货 |
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| D260008-0100 | 100 ul | 现货 |
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| D260008-0200 | 200 ul | 现货 |
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产品描述
概述
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | O14727 |
| 靶点基因 ID | 317 |
| 靶点全称 | Apoptotic protease-activating factor 1 |
| 靶点别名 | CED4 |
| 靶点研究领域 | Cancer, Metabolism |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
