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Order NO. D260157
兔抗CDC6多克隆抗体
英文名 Anti-CDC6 rabbit polyclonal antibody
别名 CDC18L, HsCDC6, HsCDC18
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 CDC6
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D260157-0025 25 ul 现货
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D260157-0100 100 ul 现货
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D260157-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q99741
靶点基因 ID 990
靶点全称 cell division cycle 6
靶点别名 CDC18L; HsCDC6; MGORS5; HsCDC18
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using D260157(CDC6 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using D260157(CDC6 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: K562 cells, Primary antibody: D260157(CDC6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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