Order NO. D260290
产品描述
概述
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P25101
|
靶点基因 ID |
1909
|
靶点全称 |
endothelin receptor type A
|
靶点别名 |
ETA; ET-A; ETAR; ETRA; MFDA; ETA-R; hET-AR
|
靶点研究领域 |
Signal Transduction, Cancer, Cardiovascular, Metabolism
|
亚型 |
Immunogen-specific rabbit IgG
|