Order NO. D260428
产品描述
概述
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P10912
|
靶点基因 ID |
2690
|
靶点全称 |
growth hormone receptor
|
靶点别名 |
GHBP; GHIP
|
靶点研究领域 |
Signal Transduction, Cancer, Developmental Biology
|
亚型 |
Immunogen-specific rabbit IgG
|