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Order NO. D260511
兔抗IL15RA多克隆抗体
英文名 Anti-IL15RA rabbit polyclonal antibody
别名 CD215
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 IL15RA
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D260511-0025 25 ul 现货
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D260511-0100 100 ul 现货
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D260511-0200 200 ul 现货
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产品描述

概述

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q13261
靶点基因 ID 3601
靶点全称 interleukin 15 receptor subunit alpha
靶点别名 CD215
靶点研究领域 Signal Transduction, Cancer, Metabolism
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D260511(IL15RA Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D260511(IL15RA Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Mouse spleen tissue, Mouse fat tissue, Mouse lung tissue, Human placenta tissue, Rat liver tissue lysates, Primary antibody: D260511(IL15RA Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds
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