网 站
反 馈
网 站
指 南
Order NO. D260585
兔抗MAP3K5多克隆抗体
英文名 Anti-MAP3K5 rabbit polyclonal antibody
别名 ASK1, MEKK5, MAPKKK5
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 MAP3K5    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D260585-0025 25 ul 现货
加入购物车
D260585-0100 100 ul 现货
加入购物车
D260585-0200 200 ul 现货
加入购物车

属性

Background: Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, IHC
Name of antibody: MAP3K5
Immunogen: Synthetic peptide of human MAP3K5
Full name: mitogen-activated protein kinase kinase kinase 5
Synonyms: ASK1; MEKK5; MAPKKK5
SwissProt: Q99683
ELISA Recommended dilution: 2000-5000
IHC positive control: Human liver cancer
IHC Recommend dilution: 50-200
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D260585(MAP3K5 Antibody) at dilution 1/50. (Original magnification: ×200)
    我的购物车(0) 结算