Order NO. D260585
兔抗MAP3K5多克隆抗体
| 英文名 | Anti-MAP3K5 rabbit polyclonal antibody | ||
| 别名 | ASK1, MEKK5, MAPKKK5 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | MAP3K5 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D260585-0025 | 25 ul | 现货 |
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| D260585-0100 | 100 ul | 现货 |
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| D260585-0200 | 200 ul | 现货 |
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属性
| Background: | Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, IHC |
| Name of antibody: | MAP3K5 |
| Immunogen: | Synthetic peptide of human MAP3K5 |
| Full name: | mitogen-activated protein kinase kinase kinase 5 |
| Synonyms: | ASK1; MEKK5; MAPKKK5 |
| SwissProt: | Q99683 |
| ELISA Recommended dilution: | 2000-5000 |
| IHC positive control: | Human liver cancer |
| IHC Recommend dilution: | 50-200 |
相关文档
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Sample Application
