Order NO. D260613
产品描述
概述
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
P33527
|
| 靶点基因 ID |
4363
|
| 靶点全称 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
|
| 靶点别名 |
MRP, ABCC, GS-X, MRP1, ABC29
|
| 靶点研究领域 |
Metabolism, Cancer, Cardiovascular
|
| 亚型 |
Immunogen-specific rabbit IgG
|
